Buscar
Mostrando ítems 1-10 de 2460
RNA activation: A diamond in the rough for genome engineers
(Wiley-liss, Div John Wiley & Sons Inc, 2017-06)
The ability to develop efficient and versatile technologies for manipulating gene expression is a fundamental issue both in biotechnology and therapeutics. The endogenous RNA interference (RNAi) pathway which mediates gene ...
Use of small interfering RNA (siRNA) as a viral replication inhibitor of Human Herpesvirus 1 in BALB/C mice with keratoconjuntivitis
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
vtRNA2-1/nc886 produces a small RNA that contributes to its tumor suppression action through the microRNA pathway in prostate cancer
(MDPI, 2020)
vtRNA2-1 is a vault RNA initially classified as microRNA precursor hsa-mir-886 and recently proposed as “nc886”, a new type of non-coding RNA involved in cancer progression acting as an oncogene and tumor suppressor gene ...
Targeting riboswitches with synthetic small RNAs for metabolic engineering
(2021-11-01)
Our growing knowledge of the diversity of non-coding RNAs in natural systems and our deepening knowledge of RNA folding and function have fomented the rational design of RNA regulators. Based on that knowledge, we designed ...
Genome-wide identification and characterization of tRNA-derived RNA fragments in land plants
(2017-01-01)
Key message: The manuscript by Alves et al. entitled “Genome-wide identification and characterization of tRNA-derived RNA fragments in land plants” describes the identification and characterization of tRNAderived sRNA ...
Reprogramming of small noncoding RNA populations in peripheral blood reveals host biomarkers for latent and active Mycobacterium tuberculosis infection
(American Society for Microbiology, 2019)